L-741,626 (Dopamine D2 Receptor Antagonist, L-741,626, L-741626, L741626), CAS [[81226-60-0]]

Catalog Number: USB-217501
Article Name: L-741,626 (Dopamine D2 Receptor Antagonist, L-741,626, L-741626, L741626), CAS [[81226-60-0]]
Biozol Catalog Number: USB-217501
Supplier Catalog Number: 217501
Alternative Catalog Number: USB-217501-10
Manufacturer: US Biological
Category: Biochemikalien
Selective dopamine D2 receptor antagonist that is shown to reversibly block agonist-induced activation of GIRK currents. Reported to have a 15-fold selectivity for D2R over D3R in vitro. Inhibition of 3H-spirperone binding to cloned rat Dopamine receptors show the following Ki values: D2R (7.1nM), D3R (155nM), D4R (596nM). Commonly used D2 inhibitor in addiction research. CAS No: 81226-60-0 Molecular Formula: C20H21ClN2O Solubility: DMSO Primary Target: D2 Primary Target Ki: 7.1nM Storage and Stability: May be stored at 4C. For long-term storage, aliquot and store at 4C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Purity: 99% (HPLC)
Form: Supplied as a white solid.
CAS Number: [81226-60-0]