Ursolic acid is a pentacyclic triterpenoid that is found in plants, such as apple peel. Ursolic acid has been shown to be a potent inhibitor of the epidermal growth factor receptor (EGFR) and the constitutive androstane receptor (CAR), two nuclear receptors that are involved in regulating cellular proliferation and inflammation. This compound has been shown to inhibit cancer cell growth by blocking these receptors. Ursolic acid also inhibits NF-kappaB, an inflammatory regulator, which may help with inflammatory diseases such as asthma or arthritis. Synonyms: (3beta)-3-Hydroxy-urs-12-en-28-oic Acid, (+)-Ursolic Acid, Bungeolic Acid, Malol, Merotaine, Neoage UR, Prunol, NSC 167406, NSC 4060, beta-Ursolic Acid CAS No: 77-52-1 Molecular Formula: C30H48O3 Molecular Weight: 456.70 Appearance: White to off-white powder Purity: 98% Identity (1H NMR): Conforms to structure Melting Point: >271C (dec.) Solubility: DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly) Storage and Stability: Store at -20C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
456.7
Purity:
98%
Form:
White to off-white powder
CAS Number:
[77-52-1]
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