Oligosaccharide domain of the monosialylated glycosphingolipid GM1, which is a major ganglioside in neuronal and glial membranes in the central nervous system. GM1 oligosaccharide interacts and modulates tyrosine kinases such as neural tropomyosin receptor kinase A (TrkA) and the epidermal growth factor receptor (EGFR). The compound is also found in epithelial membranes and is a key element for bacterial toxicity and viral infection since it acts as a receptor for the B-subunits of heat labile toxin, cholera toxin, rotavirus, and simian virus 40. It also has the ability to bind amyloid-beta proteins and is involved in Alzheimers pathogenesis. Synonyms: GM1-oligosaccharide CAS No: 52659-37-7 Molecular Formula: C37H62N2O29 Molecular Weight: 998.88 Appearance: White to off-white powder Purity: 95% Storage: 4C
Molecular Weight:
998.88
Purity:
95%
Form:
White to off-white powder
CAS Number:
[52659-37-7]
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