CD79B, Recombinant, Human, aa29-159, His-Tag (B-cell Antigen Receptor Complex-associated Protein beta Chain Isoform 1, AGM6, B29, IGB)

Catalog Number: USB-377747
Article Name: CD79B, Recombinant, Human, aa29-159, His-Tag (B-cell Antigen Receptor Complex-associated Protein beta Chain Isoform 1, AGM6, B29, IGB)
Biozol Catalog Number: USB-377747
Supplier Catalog Number: 377747
Alternative Catalog Number: USB-377747-50
Manufacturer: US Biological
Category: Molekularbiologie
CD79B, as known as B-cell antigen receptor complex-associated protein beta chain isoform 1, is B- cell-specific glycoprotein B29. It is a single-pass type 1 membrane protein containing one Ig-like V-type domain and one ITAM domain. This protein is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR). CD79A and B proteins are required for BCR- meditated signaling and consequently for the development and activation of B lineage cells. Recombinant protein corresponding to aa29-159 from human CD79B, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~16.3kD (140aa), 18-28kD (SDS-PAGE under reducing conditions.) Amino Acid Sequence: MCDLPQTHSL GSRRTLMLLA QMRRISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight: 16.3
NCBI: 000617
UniProt: P40259
Purity: ~90% (SDS-PAGE). Endotoxin: 1EU/ug (LAL).
Form: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.