Rimacalib, CAS [[215174-50-8]]

Product Overview

• Article Name: Rimacalib, CAS [[215174-50-8]]
• Biozol Catalog Number: USB-464725
• Supplier Catalog Number: 464725
• Alternative Catalog Number: USB-464725-5
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

Rimacalib, a inhibitor of CaMKII, inhibits VEGF expression in human acute monocytic leukemia cell and SF macrophage obtained from patient with rheumatoid arthritis. This effect may contribute to the anti-arthritic effects of Rimacalib. The IC50s of Rimacalib are ~1uM for CaMKIIalpha to ~30uM for CaMKIIgamma. Synonyms: SMP 114, N-[3-[(1S)-1-(2-Fluoro[1,1-biphenyl]-4-yl)ethyl]-5-isoxazolyl]-4-morpholinecarboximidamide CAS No: 215174-50-8 HCl Salt: 215174-78-0 Molecular Formula: C22H23FN4O2 Molecular Weight: 394.44 Appearance: Supplied as a off-white to pale orange solid Purity: 99% Melting Point: >56C (dec.) Solubility: Chloroform (Slightly), Methanol (Slightly), DMSO (125mg/ml) Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 394.44
• Purity: 99%
• Form: Supplied as a off-white to pale orange solid
• CAS Number: [215174-50-8]