Cepharanthine is a bisbenzylisoquinoline alkaloid from tubers of Stephania sp. first reported by Japanese researchers, Kondo and Keimatsu, in 1938. Cepharanthine exhibits a wide range of biological activities, including anti-inflammatory, antitumor, cytoprotective and antibacterial. Cepharanthine inhibits AMP-activated protein kinase (AMPK) and NFkappaB signaling pathways. Cepharanthine has been used as a therapeutic agent in Japan since the 1950s. Source: Stephania sp. Synonyms: (+)-Cepharanthine, Cepharanthin, Cepharantin, O-Methylcepharanoline CAS No: 481-49-2 Molecular Formula: C37H38N2O6 Molecular Weight: 606.7 Appearance: White solid Solubility: Methanol, DMSO. Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with methanol or DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight:
606.7
CAS Number:
[481-49-2]
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