Tubulin, beta 3 (Tubulin beta III, TUBB 3, TUBB3, Neuron Specific beta III Tubulin, beta-4, MC1R, Tubulin beta 4, TUBB 4), IgG1, Clone: [2Q121 TU-20], Mouse, Monoclonal
Catalog Number:
USB-T9155-10
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| Article Name: | Tubulin, beta 3 (Tubulin beta III, TUBB 3, TUBB3, Neuron Specific beta III Tubulin, beta-4, MC1R, Tubulin beta 4, TUBB 4), IgG1, Clone: [2Q121 TU-20], Mouse, Monoclonal |
| Biozol Catalog Number: | USB-T9155-10 |
| Supplier Catalog Number: | T9155-10 |
| Alternative Catalog Number: | USB-T9155-10-100 |
| Manufacturer: | US Biological |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | ELISA, IHC, IP, WB |
| Immunogen: | Synthetic peptide corresponding to amino acids 443-450, ESESQGPK, of human class 3 beta-tubulin conjugated to KLH. Epitope: C-terminus. |
| Class 3 beta tubulin (beta 3-tubulin) is a vertebrate tubulin Isotype specific to the neurons and mammalian testis cells, making it an ideal neuronal marker. Overexpression of class 3 beta tubulin is associated with the resistances of microtubule- targeted cancer drugs in lung cancer cell lines, breast cancer cell lines, and ovarian tumors. Applications: Suitable for use in Immunoprecipitation, Immunocytochemistry, Immunohistochemistry, Western Blot and ELISA. Other applications have not been tested. Recommended Dilutions: Immunocytochemistry (Fixed): 1:100-1:500. Immunohistochemistry (FFPE): 1:20-1:100. Requires HIER using sodium citrate buffer pH6.0 prior to staining. Western Blot: 1:1000. Optimal dilutions to be determined by the researcher. Positive Control: Brain tissue or neurons of any type. Negative Control: Non-neuronal tissue or Astrocytes. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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