Gold Nanoparticles from nanoComposix

Assay Developement, Plasmonics, Diagnostics, Biosensors, & Drug Delivery

The reliability of lateral flow assays, as used in antibody and antigen rapid test kits, and pregnancy tests i.a., depends on the quality of the components used. Our partner NanoComposix is a global leader in this field and supplies a wide range of components for assay development and research not only for lateral flow assay developement but also for Plasmonics, Diagnostics, Biosensors, & Drug Delivery. One focal point of the product range are Gold Nanoparticles.

Since 2004, nanoComposix has provided monodisperse and unagglomerated metal and metal-oxide nanomaterials to thousands of customers. Hundreds of different variants of material, size, shape, and surface are available as stock products and they have produced over 2000 custom core/shell, biofunctionalized, fluorescent, and magnetic nanocomposites to meet client specifications.

Gold Nanoparticles

nanoComposix has one of the world’s largest libraries of precisely engineered and highly characterized gold nanoparticles including:

BioReady: Conjugation-Ready Nanoparticles

BioReady nanoparticles are optimized for binding biomolecules to the nanoparticle surface. The nanoparticle conjugates are used in rapid diagnostic testing and sensing applications such as lateral flow immunoassays. To make a reporter particle selection follow these guidelines:

BioReady

For the highest sensitivity in rapid diagnostic tests use 150 nm carboxyl gold nanoshells for covalent binding to proteins.
If you just need the increased stability, reduced antibody costs, higher sample matrix stability, and more reproducible conjugates provided by covalent binding chemistry use 40 nm or 80 nm carboxyl gold nanoparticles

We always recommend starting with our conjugation kits since they include all of the components necessary for rapid success.

>> BioReady Gold Nanoparticles

>> BioReady Conjugation Kits

>> BioReady Gold Nanoshells with Citrate for passive conjugation

Ultra Uniform Highly Monodisperse Nanoparticles

For applications requiring the highest uniformity in size and shape, Nanocomposix' Ultra Uniform gold nanoparticles have a nearly perfect spherical shape, smooth surfaces, and impressively narrow size distributions (CV < 5%). The particles are used as reference standards for size and number, for TEM calibration and as biological labels.

Ultra Uniform

Ultra narrow size distribution aggregation free
Extensively characterized
Available in diameters of 10, 30, 50 and 100 nm, provided at a concentration of 0.05 mg/mL in a 2 mM sodium citrate solution

>> Ultra Uniform gold nanospheres

Golds Nanoshells

Magnetic gold nanoshells (mGNS) combine the plasmonic properties of gold nanoparticles with the separation capabilities of a superparamagnetic core. This unique synergy of material properties unlocks many different applications within the fields of diagnostics and therapeutics. The unique optical properties of the gold shell drive enhanced sensitivity in applications such as biosensors, SERS, immunodiagnostics, and photothermal therapy, while the magnetic properties of the particle core enable applications in target concentration or depletion, as well as targeted delivery in vivo.

nanoComposix gold nanoshells are trusted across diagnostics, biosensing, and plasmonic research for their sensitive optical response, stability, and reproducible performance. Whether you're developing assays, optimizing formulations, or advancing nanomaterials research, consistent particle quality is essential to achieving reliable results.

BioReady gold nanoshells are ultrabright reporter particles for molecular diagnostics. Proteins can be covalently bound to the surface of carboxyl gold nanoshells using EDC/NHS chemistry.

>> Browse nanocomposix' Gold Nanoshells

Gold Nanorods

Gold nanorods are surface plasmon resonant (SPR) rod-shaped nanoparticles with narrow size distributions and uniform shape. The gold nanorods have absorption peaks that are tunable throughout the visible and short wave near-infrared (SWNIR) regions of the electromagnetic spectrum. The used purification methods remove ammonium surfactants used during synthesis and replace it with citrate, producing a stable, easily displaceable surface chemistry to use as a base for functionalization with a wide variety of molecules (silica, DNA, antibodies, etc.). Also available are PEG-functionalized nanorods, as well as carboxyl-terminated surfaces for bioconjugation.

nanoComposix gold nanorods deliver exceptional stability, tunable optical properties, and reproducible performance for biosensing, nanomedicine, and plasmonic research. Available with peak resonances at 650, 808, and 980 nm to match common laser wavelengths, they provide reliable, batch-to-batch consistency for assay development, formulation optimization, and advanced nanomaterials research.

>> Browse Gold Nanorods

Gold Nanospheres

nanoComposix gold nanospheres are trusted across diagnostics, biosensing, drug delivery, and plasmonic research for their stability, biocompatible properties, and reproducible performance. Whether you're developing assays, optimizing formulations, or advancing nanomaterials research, consistent particle quality is essential to achieving reliable results.

nanoComposix Ultra Uniform gold nanospheres are trusted as reference standards and biological labels due to their <5% CV, precise optical properties, and reproducible performance. Whether you're calibrating instruments, developing assays, or advancing nanomaterials research, consistent particle quality is essential to achieving reliable results.

>> Browse Gold Nanospheres

Custom Particles and Lateral Flow Assay Product Development Service

Whether you are a global IVD company or a virtual start-up, developing and commercializing a lateral flow assay can present many challenges. Maybe you’re not able to achieve the clinically relevant range of your analyte, require extra manufacturing capacity to meet increased demand, or have a concept for an assay but need a trusted, experienced partner to make it a reality.

Nanocomposix is a full-service lateral flow development company specializing in the design and manufacture of ultra-sensitive quantitative diagnostic assays. Services span all phases of the development cycle from feasibility to manufacturing. Nanocomposix also offer industry-leading technologies for increasing assay sensitivity as well as starter kits to help you build and optimize your lateral flow assay.

Fill out our Service Request form and we will provide you with a quote.