Upcoming webinars in fall
Cancer Research, Multiplex-IHC, ChIP-seq
In times of contact restrictions and limited freedom to travel, online webinars are a great way to learn more and stay in touch with professional colleagues. Together with our partners and experts from diverse fields, we regularly present you upcoming webinars of interest. Have a look what is in for you this fall.
CUT&Tag vs ChIP-Seq - From Data Generation to Analysis.
Presented by Active Motif
Date: Tuesday, 21th September, at 05:30 pm (CEST)
This free webinar will discuss the best ways to generate quality data using advanced, epigenomics techniques including CUT&Tag and ChIP-Seq, and then efficiently process and interpret epigenomic data using streamlined analysis pipelines. The webinar will be given in two parts.
I. Generation and Analysis of Epigenomics Data
Speaker: Sarantis Chlamydas, Ph.D., Senior Market Development Manager- Active Motif, Inc.
Thanks to modern high-throughput techniques like ChIP-Seq, CUT&Tag, ATAC-Seq, and RNA-Seq, the potential of personalized medicine is becoming more accessible.
In this webinar we will:
- Outline Active Motif’s novel tools, epigenetic reagents, and end-to-end services
- Discuss a series of data generated by our scientists for drug discovery and human disease research
- Cover tips and tricks on how we support the generation and analysis of “Epigenomics” data into clinical diagnosis and treatments
II. Bioinformatics Breakdown – CUT&Tag vs ChIP-seq
Speaker: Amit Sinha, Ph.D., CEO - Basepair Tech
CUT&Tag is emerging as the go to technology for epigenomic profiling. The promise of higher signal from lesser cells with a high throughput is irresistible. From a birds eye view the data analysis steps and tools used look very similar between CUT&Tag and ChIP-Seq. However, a closer look will expose the differences in analysis especially with regard to parameters used.
In our discussion we will cover:
- The data processing steps – similarities and differences
- The two main peak calling tools available – MACS and SEACR
- Interpreting the values and results from each step in the analysis
Multiplex Immunohistochemistry — Expand Your Insights, Improve Your Results
Presented by Vector Laboratories
Date: Wednesday, 22nd September, at 06:00 pm (CEST)
Speaker: Craig Pow, PhD, Director of Technical Services
Clear localization of two or more target antigens on a tissue section offers investigators deep insights about gene expression, spatial relationships, and disease states. Achieving reliable and meaningful multiple antigen staining on the same section, often referred to as multiplexing, involves careful selection of the detection reagents to avoid interference between the labels and ambiguous results. This webinar will help investigators looking to establish multiplex immunohistochemistry (IHC) in their lab and investigators looking to obtain consistency with the approach.
Topics to be covered include:
- Getting started with multiplex IHC
- Reagent selection to avoid cross-reactivity
- Appropriate controls
- Counterstaining and co-localization considerations
Genetic and Metabolic Determinants of Tumor Evolution and Metastasis
Presented by GeneTex
Date: Tuesday, 28th September, at 05:30 pm (CEST)
Speaker: Dr. Bryan Duy-Anh Ngo, Memorial Sloan Kettering Cancer Center
Dr. Bryan Ngo’s research focuses on dissecting the complex interplay between genomic instability, nutrient constraints, and metabolic synthetic processes that impact the ability of a cancer cell to survive and proliferate in diverse metastatic tissue environments. In this webinar, he will describe two independent studies that (1) connect a form of genetic instability, namely chromosomal instability (CIN), with its causal role in inflammation-driven metastasis, and (2) uncover a novel therapeutic paradigm that exploits the interplay between extracellular nutrient availability and cell-intrinsic glucose-derived serine synthesis in the context of brain metastasis. Dr. Ngo’s work is expanding our knowledge of how chromosomal instability, innate immune signaling, and cancer metabolism drive metastasis, and how this insight can potentially offer new therapeutic approaches to treat metastatic disease.
Recorded webinars from the past are to find in our scientific content area.