Mouse Cell Specific Depletion Antibodies

for in vivo use

Bio X CellBio X Cell offers monoclonal antibodies to mouse cell surface proteins, that are intended for in vivo cell specific depletion studies. in vivo cell specific depletion experiments are used to establish the role of a specific cell type in diverse immunological processes and diseases. These experiments are useful to extend and confirm results obtained with genetic knock-out mouse strains or to provide information about the biological relevance of a certain cell type.

Bio X Cell's depletion antibodies mediate cell depletion through multiple mechanisms including antibody-dependent cellular cytotoxicity (ADCC), complement-dependent cytotoxicity (CDC), and antibody-dependent cellular phagocytosis (ADCP).

 

Cell Type Product Description InVivoMab InVivoPlus

B Cells

B Cells

Anti-Mouse B220, IgM, Clone [RA3.3A1/6.1] BXC-BE0067  
Anti-Mouse CD19, Clone [1D3] BXC-BE0150  

T Cells

T Cells

Anti-Mouse CD3epsilon, Clone [145-2C11] BXC-BE0001-1 BXC-BP0001-1
Anti-Mouse Thy1.2 (CD90.2), Clone [30H12] BXC-BE0066 BXC-BP0066
Anti-Mouse Thy1.1 (CD90.1), IgG2a, Clone [19E12] BXC-BE0214  
Anti-Mouse Thy1 (CD90), IgG2a, Clone [M5/49.4.1] BXC-BE0076  
Anti-Mouse TCRbeta, Clone [H57-597 HB-218] BXC-BE0102  

CD4+ T Cells

CD4+ T Cells

Anti-Mouse CD4, Clone [GK1.5] BXC-BE0003-1 BXC-BP0003-1
Anti-Mouse CD4, IgG2b, Clone [YTS 191] BXC-BE0119  

CD8+ T Cells

CD8+ T Cells

Anti-Mouse CD8alpha, Clone [2.43] BXC-BE0061 BXC-BP0061
Anti-Mouse CD8alpha, Clone [53-6.7] BXC-BE0004-1 BXC-BP0004-1
Anti-Mouse CD8alpha, Clone [YTS169.4] BXC-BE0117 BXC-BP0117
Anti-Mouse CD8 (Lyt 2.1), IgG2a, Clone [116-13.1 HB-129] BXC-BE0118  
Anti-Mouse CD8beta (Lyt 3.2), Clone [53-5.8] BXC-BE0223  

TReg Cells

TReg Cells

Anti-Mouse CD25 (IL-2Ralpha), Clone [PC-61.5.3] BXC-BE0012 BXC-BP0012

γδ T Cells

γδ T Cells

Anti-Mouse Vgamma2 TCR, Clone [UC3-10A6] BXC-BE0168  

ILCs

ILCs

Anti-Mouse Thy1.2 (CD90.2), Clone [30H12] BXC-BE0066 BXC-BP0066

NK Cells

NK Cells

Anti-Mouse NK1.1, Clone [PK136] BXC-BE0036 BXC-BP0036
Anti-Mouse CD122 (IL-2Rbeta), Clone [TM-Beta 1] BXC-BE0298  

Neutrophils

Neutrophils

Anti-Mouse Ly6G, Clone [1A8] BXC-BE0075-1 BXC-BP0075-1
Anti-Mouse Ly6G/Ly6C (Gr-1), Clone [RB6-8C5] BXC-BE0075 BXC-BP0075
Anti-Mouse Ly6G/Ly6C, Clone [NIMP-R14] BXC-BE0320  

Eosinophils

Eosinophils

Anti-Mouse/Human IL-5, Clone [TRFK5] BXC-BE0198  
Anti-Mouse CCR3 (CD193), Clone [6S2-19-4] BXC-BE0316  

Macrophages

Macrophages

Anti-Mouse CSF1R (CD115), Clone [AFS98] BXC-BE0213 BXC-BP0213
Anti-Mouse F4/80, IgG2b, Clone [CI:A3-1] BXC-BE0206  
Anti-Mouse Ly6C, IgG2a, Clone [MONTS-1] BXC-BE0203  

Monocytes

Monocytes

Anti-Mouse Ly6G/Ly6C (Gr-1), Clone [RB6-8C5] BXC-BE0075 BXC-BP0075
Anti-Mouse CSF1R (CD115), Clone [AFS98] BXC-BE0213 BXC-BP0213
Anti-Mouse F4/80, IgG2b, Clone [CI:A3-1] BXC-BE0206  

Plasmacytoid

Dendritic Cells

Plasmacytoid Dendritic Cells

Anti-Mouse CD317 (BST2, PDCA-1), Clone [927] BXC-BE0311  

Mast Cell

Mast Cell

Anti-Mouse c-Kit (CD117), IgG2b, Clone [ACK2] BXC-BE0293  

 

More Information on Bio X Cell in vivo functional antibodies:

31.01.2023

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